Drex catches his sort of girlfriend making out with a tattooed drug dealer at a party. Later, his roommate Matt finds Drex drowned, but alive in a bathtub. After getting hit by a bus and put into the morgue, Drex meets med student Cassie.

Drex explains the events of the previous evening to Cassie, and Matt makes plans to turn Drex's zombie life into an online phenomenon with his video camera.

Cassie offers Hypostatsis-Hematosis as an explanation for Drex's condition, and the search begins for Mystery Pill Guy (the tattooed drug dealer from the party).

Drex starts a new job and meets his weird cubicle neighbor Andy (Wayne Knight). He also receives an inter-office IM that asks him if he "woke up dead".

Drex arrives back home to Matt and Cassie, only to be fed calf brains by Matt as an experiment. Outside, we find that there's a van watching Drex's every move.