"Trauma" is an intense, action-packed look at one of the most dangerous medical professions in the world: first responder paramedics. When emergencies occur, the trauma team from San Francisco City Hospital is first on the scene, traveling by land, by sea or by air to reach their victims in time. From the heights of the city's Transamerica Pyramid to the depths of the San Francisco Bay, these heroes must face the most extreme conditions to save lives -- and give meaning to their own existence in the process. In this initial installment, tragedy hits close to home, and the lives and paths of the team are forever changed.

The team responds to a major accident when a car loses control and crashes into a local street fair. Meanwhile, Nancy gets a new partner, and Rabbit teaches Marisa a lesson.

Boone's marital problems take a back seat to a mad gunman who goes on a shooting rampage inside an office building. The incident forces Rabbit and Nancy to work together for the first time in over a year to treat the injured hostages. Meanwhile, Marisa realizes she's more like Rabbit than she would care to admit.

Tyler and Boone respond to an explosion at a Chinese restaurant and find that there is more to the situation than meets the eye. Meanwhile, Nancy's advanced medical training is put to the test. Elsewhere, Rabbit has an unexpected reaction to a bumpy flight.

Tyler and Boone are on the scene when chaos erupts at a Halloween party. Meanwhile, Nancy and Glenn's shift takes an unusual turn. Elsewhere, a secret is revealed that can change a partnership.