Yuri is in town all dressed up for a date when a dying agent from the 3WA (World, Welfare, and Works Agency) hands her a special card to give to headquarters. Yuri is reluctant to take it until some guys in blue uniforms arrive and chase her down. She passes the card to her reluctant partner Kei, but somehow the blue uniform guys grab it. Kei and Yuri go after the guys, but also have to evade them when the girls secure the card, and they end up having to go through some bad sections of town, leaving a wake of destruction along the way.

Kei and Yuri are at an airport, escorting some guys to the plane, but the guys get shot. The girls pursue the assassin, who turns out to be a beautiful but very skilled woman named Lady Flair. After failing to capture her, they notice that she has been apprehended by the Military Police. But Kei doesn't buy that idea, and they storm the military base later, where they are developing giant spider-like robots.

After spotting bigwig Waldess at his GCN corporation, Kei tries to confront him but the bodyguards apprehend her and toss her out. Frustrated, Kei has had enough, and resigns. Yuri is assigned to protect a neuroscientist, but runs into trouble as Lady Flair storms in to kill the scientist. Waldess takes a sabbatical to a cruiser ship on a planet's ocean full of deadly whirlpools. Kei pursues her but gets into trouble as Lady Flair is aboard the ship, and Yuri pursues to try to help out.

Professor Kupps has made it to 3WA headquarters but he has hidden himself mind-wise in a virtual reality role-playing world of his own creation. It'll be up to Yuri to go in there and save him. Kei leaves headquarters but notices the blue uniformed men from the first episode on the subway, and they are plotting to attack 3WA and kill Kupps. As Yuri enters a stronghold and fights fantasy monsters in the virtual realm, Kei gets dragged into 3WA headquarters.

With Kaps's testimony, the GCN is being investigated. The guys that represent Lucifer decide that Waldess is too dangerous especially when he's still going after Siren, so they hire an assassin, who is none other than Lady Flair! Kei gets her gun repaired but it got confiscated by the 3WA. Meanwhile, Yuri gets a new ditzy partner named Lilly, and they have to help Unit 9 stake out Waldess at a spaceport, but trouble arises when other assassins make their moves against Waldess.