At the end of Tung Han dynasty, there was plague everywhere. A doctor CHEE and his family escaped to Chukzhoug. CHEE and his son TOR practised doctor on street. A famous doctor KING used a red string to feel a girl’s pulse. TOR admired him very much. Because CHEE did not teach TOR medical art, he requested KING to be his master. A swindler PU cheated KWAN YU’s neighbor LAM. KWAN argued with PU but was sent to prison. On the other side, TOR realized KING’s eldest daughter MIU was his fiancee. However, MIU did not have good impression on him. TOR then threatened her to introduce him to KING to be apprentice. KWAN had beaten PU seriously but TOR saved him. TOR promised KWAN that he could cure LAM in order to exchange PU’s life. After several tests, TOR was able to be KING’s apprentice. When TOR was curing LAM, he noticed pestilence was spreading quickly.

TOR intruded into KING’s study and peeped at medical books. KING was angry and asked district magistrate to lock him in prison. KWAN came and could not find TOR. He demanded KING to cure LAM. After checking LAM’s pulse, KING recognized TOR’s word was true. He ran away immediately but MIU realized it. She bailed TOR out. CHEE found that two schools of medical theory might cure pestilence. In medical cottage, an official told KING to cure his father’s pestilence within two days. KING found it was difficult. Meanwhile, TOR came and asked to teach him the theory of typhus. KING promised if TOR could find a method to cure pestilence. Sound of gong and drum was coming from TOR’s room, everybody thought TOR was able to get the method.

KING’s two younger daughters LAN and WAI got two pigs for TOR as experiment, but they could not find him. The official’s father was dead and KING blamed on TOR. MIU believed TOR was not faithless. KING was worried the official would revenge on him. PU instigated him to play a lousy act about the god of plague, which villagers believed that donation could stop plague. With CHEE’s help, TOR, MIU and KWAN were able to find a special herb as an ingredient of a prescription. LAM’s pestilence was finally cured. On the other hand, the wicked plot of KING and PU.

PU thought he had pestilence. He therefore returned money to villagers hoping TOR would cure him. Due to poor business, KING and his family moved to Loyang. Moreover, CHEE wanted TOR to enter the imperial medical college in Loyang. He also told him that CHO CHO had saved him before. KING, CHEE and others stopped at Hsuchang. KING’s friend NG treated KING and his family. NG admired MIU very much. MIU asked TOR to write her love letter. TOR studied hard at home and NG chased after MIU. MIU did not see TOR for several days. She was worried and visited him. TOR was writing her love letter but it was just like a prescription. PU showed it to others. MIU was embarrassed but was happy with it.

MIU convinced TOR to work in KING’s medical cottage for their future. One day, TOR delivered medicine and passed by imperial medical college. He went in and was misunderstood as assassin. Fortunately, CHO was an understanding person and let him out. TOR also noticed CHO had hidden disease. On the street, TOR met CHO again and claimed he could cure him. However, CHO laughed away. TOR felt that he was lack of development and determined to leave. MIU borrowed money from NG helping TOR to set up his business. However, TOR always offered free medication, which put him into economic difficulty. Later, KING even came to demand TOR to repay him money. TOR then understood MIU’s grievance.