A boy arrives at the Southern Catholic Hospital Emergency Center with internal bleeding. Doctor Ham Eun Ho desperately tries to save his life and attempts to stop the internal bleeding. The surgery fails, but miraculously, the boy recovers with the power of a supernatural being. Meanwhile, the police arrest Father Jeong, and the recovering boy disappears.

Eun Ho stops Soo Min from performing an exorcism on Woo Joo and takes him back to the hospital. Certain that Woo Joo is possessed, Father Moon gets consent from the Vatican and convinces Woo Joo's mother that medical help won't help Woo Joo. When they transfer Woo Joo to another hospital, Father Moon and Soo Min take Woo Joo to a place to perform the ritual. Meanwhile, Father Jeong commits suicide in prison.

Soo Min tries to make Eun Ho believe about exorcism. After helping Woo Joo, Soo Min realizes that the evil spirit has moved onto someone else’s body. Eun Ho gets an attack from Mi So, and Father Moon finds another way to defeat the evil spirit. Later on, Father Moon decides to let Soo Min enter Mi So’s subconsciousness in order to help Mi So from the evil spirit.

Soo Min sees his dad in Mi So’s unconsciousness. Eun Ho and Soo Min perform an exorcism on Mi So under Father Moon's control. Father Moon plans that Eun Ho enters Mi So's subconscious through hypnosis and gets rid of the demon. And when being hypnotized, Soo Min sees Eun Ho in a gown.

As soon as they get rid of the devil inside So Mi’s body, a new energumen starts attacking people in the hospital. Ms. Sung gets an attack and Eun Ho sends a footage file of the incident to Soo Min and Father Moon as she finds it strange. Soo Min and Father Moon start finding the new energumen.