Camille serves Aaron with divorce papers; Phillip benches Arthur from further surgery when Arthur's resting tremor begins to endanger patients; Aaron removes a brain tumor from an elderly patient; Jeffrey and Aaron separate conjoined twins.

Jeffrey runs afoul of the trustees when a grieving husband has second thoughts after allowing him to test an artificial heart on the body of the man's newly deceased wife; Alan comes to the rescue when a patient's HMO refuses to cover Aaron's operating on her very complicated and potentially fatal brain tumor; Jeffrey visits his wife Laurie, a straitjacketed patient in a mental hospital who apologizes for drowning their son Joey; Arthur's refusal to remove his wagging finger from Jeffrey's face during an argument leaves him with a bitten digit, and enables Jeffrey to diagnose the curable medical condition that's causing Arthur's resting tremor.

Arthur nearly fires Danny for failing to adhere to triage protocol, thereby delaying the treatment of a critically injured prostitute with AIDS; Phillip becomes the acting chief of staff after Hackett suffers a fatal heart attack during a little afternoon delight with Angela in the MRI room; Jeffrey and Arthur argue over the future of a baboon with the potential to prolong the life of Jeffrey's patient with heart failure and Arthur's patient with AIDS.

Jeffrey tells Nadine about Laurie's schizophrenia and the death of his son; Aaron and Camille grieve about their impending divorce; several members of a family of trapeze artists are brought into the hospital in critical condition after a devastating accident during a circus performance; one of Aaron's former patients reveals his bigotry when he refuses to allow Nadine to remove his diseased gall bladder and insists that Aaron or another Jewish surgeon perform the procedure; Jeffrey exhibits signs of a meltdown when, in the space of a few hours, outrageous conduct in a nightclub gets him mistakenly arrested for soliciting a prostitute and he vandalizes the car of a man who stole his parking space; Phillip incorrectly attributes Aaron's angry outburst at one patient minutes after losing another young patient in surgery to tensions with Camille, and threatens to fire Camille if there's a recurrence.

Phillip's religious beliefs and Jeffrey's grief over the death of his son put them on opposite sides of whether to convince a young mother to remove her infant from life support so that her daughter's organs can be donated to save the life of another baby; Karen deflects a flirtation from Jeffrey, but romantic sparks fly between her and Aaron.