Shotz brewery bottle-cappers and best friends, Laverne DeFazio and Shirley Feeney, are invited by the boss' nephew, Tad Shotz, to the Shotz formal society party. Shirley is excited about going while Laverne finds it insulting.

While Mr. DeFazio is away for a few days, Laverne and Shirley take over running the Pizza Bowl for him. Later, The Fonz convinces the girls to let him host a wild bachelor party at the Pizza Bowl - it goes against Shirley's better judgement, but Laverne doesn't see any problem with it. When the party gets started, however, the girls both begin to realize just how much of a mess they've gotten themselves into.

During the annual Shotz bowling tournament, Laverne decides to get even with her bowling rival, Karen from the past 5 years. However, on the big night, Laverne falls ills and takes heavy medication, leaving Laverne ""jerky"" during the tournament.

While Laverne & Shirley await their yearly high school reunion, they reminisce about their old crazy friend, Anne-Marie, who shows up at the reunion a nun.

Laverne suddenly decides to marry her boyfriend of only two months before he is sent away by the Navy.