In the premiere episode, ‘Best Possible Defense,’ Kate is stunned when a woman friend, Barbara Inerson, is charged with conspiracy to commit murder, stemming from a terrorist bombing during her days as a student militant. Kate realizes that the Government is trying to force her rebellious client, Barbara, to inform on former fellow conspirators who are still underground, and who are the only witnesses to what really happened.

When a terrified homeowner shoots an armed intruder during a "wrong door" drug raid, it initially appears to be a clear case of self-defense. However, attorney Kate McShane must defend her client, Norman Kagan, against a murder charge stemming from evidence planted by a corrupt Federal agent. Narcotics inspector Brenner (guest star Clu Gulager), resentful over the fatal shooting of a colleague by Kagan, refuses to acknowledge that the raid on Kagan's home was a mistake. Consequently, Kate realizes it's her client's word against that of the government agent in court.

A burglar is killed In a trap by a scrappy old man, played by guest star Jack Gilford, who insists he is innocent of wrongdoing and demands his day in court. Angered by feisty Joe Ackerman's refusal to let Kate McShane plea bargain for him, prosecutor Harry Morrison vindictively seeks a sanity hearing and serves notice on Kate that he will spare no legal weapon at Joe's trial for manslaughter.

A pill-popping pro football star is charged with murder, but when Kate tries to defend him the powerful team management moves to get her off the case. Veteran player J.D. talks his accused buddy, Vinnie, into firing Kate, who realizes the ruthless team owner, Cervan, fears the story would come out in court.

Suspicious when her client readily confesses to a puzzling murder. Kate tries to learn what really happened and stumbles on a top-secret government operation. Despite official warnings to halt her inquiries, Kate, with help from her father and brother, uncovers facts that might clear her client but could ruin the sensitive federal investigation.