Young orphan Esther Summerson is brought to the High Court of Chancery, where she is thrown together with two wards of the court, Richard Carstone and Ada Clare. Both are caught up in the infamous suit of Jarndyce and Jarndyce, which brings nothing but ruin and despair to all it touches. Esther, Richard and Ada are sent to live at Bleak House, where they receive a friendly welcome from their rich guardian John Jarndyce.

Despite his grim discovery, Tulkinghorn remains undeterred from his ruthless inquiry into Lady Dedlock's past. A young crossing sweeper, Jo, may hold a key to the mystery. Krook discovers evidence in Nemo's room which could provide a crucial clue. Richard and Ada plan their engagement, but receive an unexpected setback. And as Richard begins a career in medicine, Esther meets an attractive young doctor called Allan Woodcourt.

As Tulkinghorn edges closer to the truth, Lady Dedlock puts her reputation at risk when she pays an undercover visit to Nemo's former haunts. John Jarndyce finds himself increasingly attracted to Esther, but Richard makes an announcement which causes him dismay. And Woodcourt has news that comes as a terrible blow to Esther.

A chance encounter in the country raises intriguing questions for Esther and Lady Dedlock. Legal clerk Guppy, still besotted with Esther, discovers surprising new information about her past and decides to dig deeper still. And Lady Dedlock's secret is far from safe, as Tulkinghorn stumbles across a lead which could destroy her reputation forever.

Richard's inability to settle causes a rift with John Jarndyce, much to Ada's dismay. Tulkinghorn finally unearths the possible identity of the mysterious Nemo. Nemo's old friend Sergeant George has the evidence he needs to prove it and Tulkinghorn will stop at nothing to force George to hand it over. But George has even more problems when Gridley turns up on his doorstep, on the run from the law and infected with the fever.