In the Costa Rican rainforest, Steve is almost strangled by a boa constrictor, is struck dumb by the strike speed of a viper, and plays hide and seek with a deadly bushmaster. Then he gets hands-on with the world's most poisonous frog, nearly gets a nip from a blood-sucking vampire and encounters a huge American crocodile.

In the heart of South America, Steve hunts for the mighty anaconda, swims with piranha and has a surprising face-to-face encounter with a creature that bit him. Steve then visits Peru to meet the giant river otter and another very formidable snake.

In Central America, Steve takes to the water in chain mail in search of a deep sea monster. Back on land he searches for the world's biggest wasp before setting off for a day of snake hunting. Then he heads to Panama to track down one of the largest birds of prey in the world: the harpy eagle. Finally, Steve handles some giant bullet ants, who possess the world's most painful insect bite.

Steve Backshall is in the Philippines for another of his best ever missions. He has a tense and intimidating encounter with a living dinosaur, and delves into a subterranean world to find an arachnid with legs four times longer than its body. An early morning dive in the beautiful waters of the Philippines rewards him with a stunning shark that spends most of the day 550 meters below the surface. There is a swim with one of the deadliest snakes on the planet, and a nocturnal search in the jungle reveals a Tarsier, a deceptively cute predator who eats its victims head first.

In South Africa, Steve confronts blacktop sharks, the mighty black eagle, and a huge swarm of killer bees. He then heads into Namibia, to encounter a sidewinder and gets hands on with the ultimate Africa predator, the lion!